Ultrafine-Grained Ti-31Mo-Type Composites with HA and Ag, Ta2O5 or CeO2 Addition for Implant Applications

Ultrafine-grained Ti31Mo alloy and Ti31Mo5HA, Ti31Mo5HA-Ag (or Ta2O5, CeO2) composites with a grain size of approximately 2 μm were produced by the application mechanical alloying powder metallurgy. Additionally, surface was modified. In first stage, specimens immersed in 5M NaOH for 24 h at 60 °C. second hydroxyapatite (HA) deposited on sample surface. The cathodic deposition −5 V vs. open circuit potential (OCP) electrolyte containing 0.25M CaNa2-EDTA (di-calcium ethylenediaminetetraacetic acid), K2HPO4 1M 120 °C applied. bulk is single β-type phase. alkali-modified titanium oxide, Ti3O formed. After hydrothermal treatment, layer mostly consists Ca10(PO4)6(OH)2 (81.23%) about 19% content CaHPO4·2H2O. Using optical profiler, roughness 2D topography parameters estimated. vitro cytocompatibility synthesized materials studied. cell lines normal human osteoblasts (NHost) periodontal ligament fibroblasts (HPdLF) conducted presence tested biomaterials. Ti-based altered HA Ag, Ta2O5 or CeO2 have superior biocompatibility than microcrystalline Ti metal. NHost HPdLF cells contact biomaterial showed stable proliferation activity. Biocompatibility tests carried out indicate that ultrafine-grained Ti31Mo5HA could be good candidate implant applications.